Remmo 20mg Tablet

✔️ Uses of Remmo 20

• Gastroesophageal Reflux Disease (Acid Reflux)
• Peptic Ulcer Disease

✔️ How to use Remmo 20

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Remmo 20 is to be taken empty stomach.

✔️ How Remmo 20 works

Remmo 20 is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

✔️ What if you forget to take Remmo 20?

• If you miss a dose of Remmo 20, take it as soon as possible.
• However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.
• Do not double the dose.

✔️ Side effects of Remmo 20

• Headache
• Dizziness
• Dryness in mouth
• Nausea
• Abdominal pain
• Constipation
• Flatulence
• Diarrhea

✔️ Missed Dosage of Remmo 20

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

✔️ Quick SUggestions:

• It is a medication that is well-tolerated and lasts a very long period.
• Avoid eating just before going to bed or in the evening.
• If you get a fever, watery diarrhea, or persistent stomach pain, call your doctor right immediately.
• Remmo 20 usage for an extended period of time may result in weak bones and a mineral deficit, especially magnesium. As directed by your doctor, get enough calcium and magnesium in your diet or as supplements.
• If you experience reduced urine, edema (swelling brought on by fluid retention), lower back discomfort, nausea, exhaustion, rash, or fever, call your doctor immediately once. These could be kidney-related symptoms.

✔️ Indications of Remmo 20mg Tablet

• Gastro-esophageal Reflux Disease (GERD) is treated with esomeprazole MUPS tablets (GERD).
• NSAID-related stomach ulcer risk is reduced.
• Eradication of Helicobacter pylori (Triple therapy).
• Idiopathic hypersecretion and Zollinger-Ellison syndrome

✔️ Pharmacology

Esomeprazole is a proton pump inhibitor that inhibits the H+/K+ ATPase in the gastric parietal cell, suppressing gastric acid output. The first single optical isomer of a proton pump inhibitor, esomeprazole (S-isomer of omeprazole), provides superior acid control than racemic proton pump inhibitors.

✔️ Dosage of Remmo 20

Inflammatory Esophagitis

• Adult (over the age of 18): 40 mg once a day for 4 weeks.
• For 4 weeks, take 40 mg once a day in children and adolescents (12 to 18 years old).

Maintaining erosive Esophagitis Healing

• Adult (over the age of 18): 20 mg once a day.
• 12 to 18-year-old children and adolescents: 20 mg once a day.

H. pylori eradication (Esomeprazole MUPS tablet with 1000 mg Amoxicillin and 500 mg Clarithromycin)-

• Adult (over the age of 18): 20 mg twice daily for seven days.
• Twelve to eighteen-year-olds: 20 mg twice daily for seven days.
• Idiopathic Hypersecretion and the Zollinger-Ellison Syndrome
• Adult (>18 years): twice daily doses of 40–80 mg.

Children aged 1 to 11:

• Erosion of the Esophagus 20 kg or less: 10 mg once every day for 8 weeks. Weight under 20 kilograms: 10 or 20 mg once daily for eight weeks.
• 10 mg once daily for the maintenance of erosive esophagitis healing

Esomeprazole MUPS pill is not recommended for usage in children under the age of one year old.

✔️ Administration of Remmo 20

Esomeprazole MUPS tablets should be swallowed whole with liquid. The tablets should not be chewed or crushed. If required, the tablets can also be dispersed in half a glass of non-carbonated water (mineral water is not suitable). No other liquids should be used. Stir until the tablets disintegrate and drink the liquid with the pellets immediately or within 30 minutes. Rinse the glass with half a glass of water and drink. The pellets must not be chewed or crushed.

✔️ Interaction of Remmo 20

CYP2C19 and CYP3A4 metabolize esomeprazole extensively in the liver. Studies conducted in vitro and in vivo have demonstrated that esomeprazole isn't likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, or 3A4. With medicines processed by these CYP proteins, no clinically important intuition would be expected. According to drug interaction studies, there are no clinically significant interactions between Esomeprazole and phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin. Esomeprazole could interfere with CYP2C19, the enzyme that is primarily responsible for metabolizing the drug. Diazepam's clearance was reduced by 45% when Esomeprazole 30 mg and diazepam, a CYP2C19 substrate, were taken together. Twelve hours after the initial dose and beyond, expanded plasma levels of diazepam have been monitored. Esomeprazole prevents caustic gastrointestinal discharge. Therefore, esomeprazole may interfere with the absorption of medications whose bioavailability is strongly influenced by gastrointestinal pH (such as ketoconazole, and press salts a).

Quinidine, diazepam, phenytoin, or verbal contraceptives shouldn't be used with Esomeprazole because they don't seem to change its pharmacokinetic profile. Clarithromycin in Combination with Other Therapies: Esomeprazole and 14-hydroxy clarithromycin plasma levels have increased as a result of co-administration with clarithromycin and amoxicillin.

✔️ Contraindications

Esomeprazole is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted Benzimidazoles.

✔️ Pregnancy & Lactation

In pregnant women, there are no sufficient and well-controlled trials. No teratogenic effects have been found in animal investigations. Esomeprazole excretion in milk has not been studied. If the use of esomeprazole is thought necessary, breastfeeding should be terminated.

✔️ Precautions & Warnings

• In patients who have a history of hypersensitivity to any of the formulations, esomeprazole is not recommended.
• If the patient has severe liver failure and renal impairment, esomeprazole should be administered with caution.

✔️ Storage Conditions

Protect from light and store in a cool, dry area below 25°C. Keep out of children's reach.